What is New in Test-Tube Baby Treatment?
Animals, birds, insects, humans — all have got life on the earth. Even after the birth, we have been gifted with many things endlessly by the nature. But, the human being is the type of living being on the earth, who is not yet satisfied with whatever he has gained from nature. He is always very much ready to get something more, something new, to do something new, to fetch new possibilities. The gorgeous development in every field of the human life is its witness.
This development is that much of tremendous — what we tell about the “birth”, and also made a challenge to the system of conventional reproduction practice. This challenge means the invention of the test-tube baby. Then too he was not out of action. He updated this invention with the latest innovations, and as a result, we have a series of better treatments: IVF, ICSI, TESA, Surrogacy……… etc.
Yet we are in half-baked surprised, yet the tradition of new innovations has not been stopped. And as one and only reason for the same, we can tell that: Even though science has made tremendous progress, yet the relationship between the embryo and the wall of the uterus has not been clear to us. That means, science yet has not reached up to the proper understanding of the factors — due to which the embryo establishes — implants with the uterus wall. So in, IVF method, even with the best treatment, we do not get 100 % success. To overcome this limitation, and to increase the success ratio, the innovations are done in IVF. The new and advanced treatment method, which we are going to discuss is its gift.
1) ICSI: Before knowing about the latest and in practice treatment methods of today and tomorrow, we should have the recapitulation on one of the important and well-established treatment methods of infertility — and this is also well-heard in reference of IVF is ICSI. The full form is — Intra Cytoplasmic Sperm Injection. ICSI is a type of the IVF. Here, the sperms of the male are inserted in the ovum with a microscopic injection.
Here, it is very clear that the sperms are directly inserted into the ovum — means the sperms do not have to be dependent on their energy (to penetrate). So, pregnancy can be conceived by even very weak and less motility having sperms. Thus, a very few number of sperms ( 4 to 5 ) are needed, so sperms can be obtained from the testes of the person having a very less sperm count also. So that, those couples can get their own child. This method is also known as a TESA. When ICSI was not discovered, there was no substitute of getting sperms from the donors for the people having no sperms (azoospermia) or very less sperms ( oligospermia). Thus, ICSI method has revolutionized in the male infertility. Here, we have to think clearly that even though there is a revolution with the advanced machines, high level of skill and experience are needed to achieve it.
Let we know about the absolute new treatments regarding IVF, — “oven- fresh”, after knowing up to this about ICSI.
2) Laser Hatching: The ovum is fertilized with the sperms and resulted in an embryo. The embryo inside the ovum, breaks the outer membrane of the ovum and implanted in the uterus — this is known as Hatching. Sometimes, the surrounding wall of the ovum is very thick and stiff. In this case, the embryo cannot come out and cannot implant with the uterus. And if there is no impregnation, how the child……….? In these circumstances, the ovum membrane is being made thinner with laser energy — guided by the computer, at one side and so the embryo can have connivance to come out from that place and it can be implanted.
If there is frequent failure in IVF, or there is IVF at the elder age, the Laser hatching is needed mostly.
3) PGD (Pre-implantation Genetic Diagnosis): Pre-implantation Genetic Diagnosis means: to diagnose the chromosomes before the implantation / establishment / adherence of the embryo. This method is used to prevent the genetic disorders like Down’s syndrome, thalassemia major, muscular dystrophy, etc. in the embryo and to prevent the child birth with physical defects.
The method is somewhat like this: In a laboratory developed 3-day-old embryo, there are 8 to 10 cells. For the diagnosis, only one cell is aspired by breaking the outer layer with the laser.
You might think — how it is possible to know about would be diseases from a single cell? But friends, the impossible-like matter is also possible with the profuse development in the field of Science and Technology. And yes, this single cell is tested in the laboratory for the genetic disorders. If it contains genetic disorder, it is not put in the uterus. 7 to 8 embryos prepared by the embryologist, every embryo is tested likewise and only 2 to 3 disease free embryos are put in the uterus. And thus, the success ratio increases.
There is also the other reason for PGD — sometimes if the implanted embryo itself is having defect, it causes the failure of IVF. In this case, with the help of the only the disease free embryo putting the success ratio increases.
4) IMSI — Super ICSI: IMSI is a new form of ICSI with some modifications. That is why it is known as Super ICSI. The full form of IMSI is: Intra-Cytoplasmic Morphologically Selected Sperm Injection. With the help of the microscope used in ICSI treatment, the picture of the male semen is seen 200 times bigger. But, here, the defected sperms are not founded immediately (at once). While with the help of advanced microscope in the IMSI method, 6000 X bigger picture available. By this huge picture, it can be discriminate the good sperms and damaged or defected sperms form the semen, easily. So only the good quality having sperms are selected form the semen. Thus, by entering quality having sperms in the ovum, the probabilities of well-developed embryo and healthy child increases a lot.
Thus, IMSI treatment is a latest step in male fertility. Likewise IMSI, IVM treatment would be a great revolution in female infertility. In IVM, the ova in the developing stage (immature ova) are taken out in certain circumstances. These immature ova are held in the culture medium for 24 to 48 hours in the laboratory. Then hormone quality is added to them and made mature. Then these mature ova are made fertilize with ICSI and is transform in the embryo. Now, likewise IVF, it is put/ implanted in the embryo.
ð Which women need IVM?
When the woman suffers from the uterus cancer, the doctor might suggest chemotherapy or radiation therapy. During this therapy, it might be needed to remove ovaries of the woman. In these cases, the ova are taken previously and screening of the good quality having ova is done — they are freeze. Then at the time of treatment, with the help of IVM, that lady can become pregnant.
The women over the age of 35 years, whose ova are weakened, the quantity of ova has been decreased in abundance, they can also go for the same type of treatment. According to the 19th June, 2011 report, there are only 400 birth occurred by this method in the world. Thus, this is the latest treatment. It is available in the foreign countries — yet not available in India, but there are sure chances of it.
In addition to above-mentioned treatments, there are the possibilities to discover the new techniques through which, during IVF, we would be able to develop high quality having embryos, so just with one embryo implantation, the child can be obtained. Consequently, the problems of twins or triplet birth, as a result of 2 to 3 implantations — today’s IVF, can be eradicated completely.
Except this, there are the possibilities of inventions of many result-oriented treatment methods. But, here it is very necessary to clarify, the machines for the use of these techniques would be highly advanced and it would be extremely expensive for the ordinary Indian couples. In addition to this, it might be one and half decade to come and to establish these methods in India.
You don’t need to feel hopeless for your pregnancy, we, Rupal Hospital, are here to help you out to learn more about the test-tube baby treatment and make you feel comfortable and relax during your treatment. Our hospital has advanced technologies and we assure you that you will have a successful pregnancy at Rupal Hospital.
To know more about us visit our website: https://rupalhospital.com/
Contact:+91 261 2700000, +91 99099 12144, +91 99138 02244
Address: Plot no. 6, Next lane to Vijay Sales,
Behind Kataria Automobiles,
Off Gaurav Path, Piplod, Surat 395007
Email: info@rupalhospital.com
